What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Oxidative stress
Mechanisms of Action
Oxidative stress is a condition where an imbalance between free radicals and antioxidants leads to cellular damage.
Mitochondria
Mechanisms of Action
increasing ATP production and supporting improved cellular repair and regeneration.
Because hair follicles are highly energy-dependent
Keratinocytes
Mechanisms of Action
Keratinocytes are cells in the epidermis responsible for producing keratin.
Cytokines
Mechanisms of Action
Cytokines are small proteins involved in cell signaling that regulate immune responses, inflammation, and tissue repair throughout the body.
