What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Hair Follicle Stem Cells
Mechanisms of Action
Hair follicle stem cells are undifferentiated cells located in the bulge region of the follicle.
Hair Cycle Dysregulation
Mechanisms of Action
Hair cycle dysregulation refers to an imbalance in the natural phases of hair growth (anagen, catagen, telogen).
Mitochondria
Mechanisms of Action
increasing ATP production and supporting improved cellular repair and regeneration.
Because hair follicles are highly energy-dependent
Dermal Papilla Cells
Mechanisms of Action
Dermal papilla cells are specialized cells located at the base of each hair follicle that regulate hair growth by interacting with surrounding stem cells and signaling molecules.
