What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Hair Cycle Dysregulation
Mechanisms of Action
Hair cycle dysregulation refers to an imbalance in the natural phases of hair growth (anagen, catagen, telogen).
Growth Factors
Mechanisms of Action
Growth factors are naturally occurring proteins that stimulate cell proliferation, differentiation, and healing.
Vasodilation
Mechanisms of Action
Vasodilation is the widening of blood vessels, resulting in increased blood flow to tissues.
Oxidative stress
Mechanisms of Action
Oxidative stress is a condition where an imbalance between free radicals and antioxidants leads to cellular damage.