What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Growth Factors
Mechanisms of Action
Growth factors are naturally occurring proteins that stimulate cell proliferation, differentiation, and healing.
Hair Follicle Stem Cells
Mechanisms of Action
Hair follicle stem cells are undifferentiated cells located in the bulge region of the follicle.
Dermal Papilla Cells
Mechanisms of Action
Dermal papilla cells are specialized cells located at the base of each hair follicle that regulate hair growth by interacting with surrounding stem cells and signaling molecules.
Nitric oxide (NO) release
Mechanisms of Action
Nitric oxide release refers to the production of nitric oxide molecules that help regulate blood flow and cellular communication.
