What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Cytokines
Mechanisms of Action
Cytokines are small proteins involved in cell signaling that regulate immune responses, inflammation, and tissue repair throughout the body.
Reactive oxygen species (ROS)
Mechanisms of Action
Reactive oxygen species (ROS) are unstable molecules containing oxygen that can cause cellular damage at high concentrations.
Nitric oxide (NO) release
Mechanisms of Action
Nitric oxide release refers to the production of nitric oxide molecules that help regulate blood flow and cellular communication.
Hair Cycle Dysregulation
Mechanisms of Action
Hair cycle dysregulation refers to an imbalance in the natural phases of hair growth (anagen, catagen, telogen).
