What is prostaglandin D2 (PGD2)?
PGD2 is a lipid compound found in higher concentrations in bald scalps and believed to inhibit hair follicle growth and regeneration.
It works by blocking the signaling pathways necessary for transitioning follicles into the active growth phase.
While red light therapy doesn’t directly suppress PGD2, it may help offset its inhibitory effects by enhancing mitochondrial function and supporting pro-growth signaling in follicle cells.
Related terms
Hair Follicle Stem Cells
Mechanisms of Action
Hair follicle stem cells are undifferentiated cells located in the bulge region of the follicle.
Growth Factors
Mechanisms of Action
Growth factors are naturally occurring proteins that stimulate cell proliferation, differentiation, and healing.
Androgen Receptors
Mechanisms of Action
Androgen receptors are proteins inside cells that bind to male hormones like testosterone and dihydrotestosterone (DHT), influencing hair follicle behavior and sensitivity.
Vasodilation
Mechanisms of Action
Vasodilation is the widening of blood vessels, resulting in increased blood flow to tissues.
